Composition
Each 1 ml contains:
- Sulphadiazine Sodium – 435 mg
- Trimethoprim – 80 mg
Pharmacological Properties
Dadprim is a synergistic combination of Sulphadiazine and Trimethoprim. Individually, both act as bacteriostatic agents, but when combined, they exert a bactericidal effect. This synergy makes Dadprim highly effective against a wide range of pathogenic bacteria, including strains resistant to common antimicrobials. It is particularly useful in addressing infections that are hard to treat due to bacterial polyresistance.
Target Species
- Poultry: chickens and turkeys
- Ruminants: calves and lambs
Indications for Use
Dadprim is effective against both Gram-positive and Gram-negative bacteria, including:
- Salmonella, Escherichia coli, Klebsiella, Proteus, Haemophilus (Coryza), Pasteurella, Clostridium, Corynebacterium, Streptococcus, and Staphylococcus.
It is also effective in the treatment of omphalitis in young animals.
Contraindications
- Do not use in laying hens producing eggs for human consumption.
- Not to be used in animals with severe hepatic or renal impairment.
- Not recommended for calves with functional rumen.
Undesirable Effects
No adverse effects are commonly observed when used at recommended dosages.
Posology and Method of Administration
Shake well before use.
- Poultry (chickens and turkeys): 1 ml per 30 kg of body weight in drinking water daily for 3–5 days (equivalent to 15 mg/kg bw of active combination).
- Calves and lambs: 1 ml per 15 kg of body weight, mixed with water or milk, daily for 5 days (equivalent to 30 mg/kg bw of active combination).
Overdose
Dadprim has a wide safety margin. Farm animals and poultry tolerate up to 5 times the recommended dose without adverse effects.
Withdrawal Period
- Chickens: 1 day
- Turkeys: 3 days
- Calves and lambs: 3 days
Special Safety Precautions for the Person Administering the Product
No specific precautions required.
Special Precautions for Storage
Store in a dry place below 30°C.
Do not refrigerate.
For veterinary use only. Consult your veterinarian before use.