Composition

Each 1 g contains:

• Tetramisole hydrochloride – 100 mg
• Excipients – q.s. to 1 g

Pharmaceutical Form

Water-soluble powder

Pharmacological Properties

Tetramisole is an effective anthelmintic that induces paralysis in nematodes through dual mechanisms:

1. Continuous stimulation of the parasite’s nervous system (cholinomimetic effect), leading to spastic paralysis.
2. Inhibition of fumarate reductase, disrupting energy metabolism essential for parasite survival.

These combined actions result in rapid and effective expulsion of gastrointestinal and pulmonary nematodes.

Target Species

Cattle, camels, sheep, goats, buffaloes, and poultry

Indications for Use

Dadmisole 10% Powder is indicated for the treatment and control of gastrointestinal and respiratory nematode infections, including:

• In ruminants and camels: Haemonchus, Ostertagia, Trichostrongylus, Cooperia, Oesophagostomum, and Dictyocaulus spp. (verminous bronchitis)
• In poultry: Capillaria, Ascaridia, and Heterakis spp.

Its broad-spectrum efficacy makes it ideal for integrated parasite control programs in both livestock and poultry.

Contraindications

Do not use in animals with known hypersensitivity to tetramisole.

Undesirable Effects

No adverse effects reported at recommended dosages.

Posology and Method of Administration

Administer orally via feed or drinking water:

• Ruminants and camels: 15–20 mg tetramisole per kg body weight as a single dose
• Poultry: 40 mg tetramisole per kg body weight in drinking water once daily for 2 consecutive days

Shake or mix well before use. Ensure uniform distribution in feed or water.

Overdose

No adverse effects observed at recommended doses. Avoid exceeding the stated dose.

Withdrawal Period

• Meat: 15 days
• Milk: Do not use in animals producing milk for human consumption
• Eggs: Do not use in layers producing eggs for human consumption

Special Safety Precautions for the Person Administering the Product

No special precautions required. Wash hands after handling the product.

Special Precautions for Storage

Store in a cool, dry, and dark place at a temperature below 30°C.
Keep out of reach of children.

For veterinary use only. Consult a veterinarian before use.