Composition
Each bolus contains:
- Chlortetracycline hydrochloride – 500 mg
Pharmaceutical Form
Bolus
Pharmacological Properties
Chlortetracycline hydrochloride is a broad-spectrum antibiotic from the tetracycline group. It is effective against a wide range of Gram-positive bacteria such as Staphylococcus, Streptococcus, and Corynebacterium, as well as Gram-negative bacteria like Escherichia coli, Klebsiella, and Proteus. Additionally, it is active against Mycoplasma and Rickettsia species.
It inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit.
Target Species
- Oral administration: large animals, pre-ruminant calves, dogs, and cats
- Intrauterine use: cattle, sheep, and goats
Indications for Use
Teteradad Bolus is indicated for the prevention and treatment of infectious diseases caused by chlortetracycline-sensitive organisms, particularly:
- Respiratory infections
- Gastrointestinal infections
- Urogenital and post-partum infections
Its intrauterine use supports recovery after parturition and helps in placental expulsion.
Contraindications
No known contraindications when used as directed.
Undesirable Effects
No undesirable effects reported under normal conditions of use.
Posology and Method of Administration
Oral administration (daily for 4–5 days):
- Large animals: 1 bolus per 50–100 kg body weight
- Pre-ruminants: 1 bolus per 25–50 kg body weight
- Dogs and cats: 25–50 mg chlortetracycline per kg body weight
Intrauterine administration (every 48 hours post-parturition):
- Cattle: 1–2 boluses
- Sheep and goats: 0.5–1 bolus
Treatment should continue until natural expulsion of the placenta.
Overdose
No adverse effects are expected in case of overdose when used according to recommended guidelines.
Withdrawal Period
- Do not slaughter animals for human consumption within 5 days of the last treatment.
- No milk withdrawal time is specified (if needed, adjust based on local regulations).
Special Safety Precautions for the Person Administering the Product
No specific precautions are required. However, it is advisable to wash hands after handling the product.
Special Precautions for Storage
- Store in a dry place below 30°C.
- Keep out of reach of children.
Packaging
- 50 boluses in PVC blister, packed in a carton box
- 20 boluses in PVC blister, packed in a carton box
For Veterinary Use Only, Consult a veterinarian before use