Composition
Each 1 ml contains:

• Ceftiofur (as hydrochloride): 50 mg

Pharmaceutical Form
Sterile oily injectable suspension for intramuscular or subcutaneous use

Pharmacological Properties
Ceftiofur is a third-generation cephalosporin antibiotic with broad-spectrum bactericidal activity against gram-positive and gram-negative bacteria. It works by inhibiting bacterial cell wall synthesis, leading to rapid bacterial death.

Following intramuscular administration, ceftiofur is quickly absorbed, achieving peak plasma concentrations within approximately 30 minutes. Due to poor oral bioavailability, it is administered by injection for optimal therapeutic efficacy.

Target Species
Beef and dairy cattle

Indications for Use
Ceftiodad Injection is indicated for the treatment of:

• Bovine respiratory disease (BRD), including pneumonia caused by Pasteurella haemolytica, Pasteurella multocida, and Histophilus somni
• Acute postpartum metritis associated with ceftiofur-sensitive pathogens
• Acute bovine interdigital necrobacillosis (foot rot) caused by Fusobacterium necrophorum and Bacteroides melaninogenicus

This product helps ensure rapid recovery, reduced economic losses, and improved overall herd health.

Contraindications

• Do not use in animals with known hypersensitivity to ceftiofur or other beta-lactam antibiotics
• Avoid injecting more than 15 ml at a single site

Undesirable Effects
Mild discoloration or localized skin reaction may occur at the injection site but usually resolves without intervention.

Posology and Method of Administration
Shake well before use.
Administer by subcutaneous or intramuscular injection as follows:

• General dosage: 1–2 ml per 45 kg body weight once daily for 3–5 days
• Postpartum metritis: 2 ml per 45 kg body weight for 5 consecutive days

Overdose
No specific adverse effects reported in cases of overdose under normal conditions of use.

Withdrawal Period

• Meat: 3 days
• Milk: Zero withdrawal time

Special Safety Precautions for the Person Administering the Product
No special precautions are required. Standard hygienic measures should be observed when handling veterinary pharmaceuticals.

Special Precautions for Storage
Store in a dry place below 30°C.
Do not refrigerate or freeze.
Keep out of reach of children.

Product Description
Off-white to yellow oily suspension

Packaging
Amber glass vial – 100 ml

For veterinary use only. Consult a veterinarian before use.