Composition

Each 1 ml contains:

• Dexamethasone sodium phosphate: 2 mg

Pharmaceutical Form

Sterile injectable solution
Appearance: clear, yellowish solution free of suspended matter

Pharmacological Properties

Dexamethasone is a synthetic corticosteroid and a potent analogue of prednisolone. It exerts strong anti-inflammatory, antiallergic, and gluconeogenic effects, in addition to a broad spectrum of hormonal and metabolic activities. Dexadad Injection provides rapid and effective relief in inflammatory and stress-related conditions in animals.

Target Species

Cattle, horses, dogs, and cats

Indications for Use

Cattle:

• Bovine ketosis: Dexadad Injection promotes gluconeogenesis, leading to rapid normalization of blood glucose levels within 6 to 12 hours (intramuscular) or earlier (intravenous). Acetone levels typically normalize within 24 hours. Improved appetite, behavior, and milk production are observed within 12 hours. Full recovery is usually seen within 3 to 7 days.
• Supportive therapy: May be used alongside appropriate treatments in cases of mastitis, metritis, traumatic gastritis, pyelonephritis, heat exhaustion, shipping fever, or pneumonia.

Horses:

• Effective in treating acute musculoskeletal inflammation such as bursitis, carpitis, osselets, tendonitis, myositis, and sprains
• Also indicated for laminitis and retained placenta, as supportive treatment after addressing the primary cause

Companion animals (dogs and cats):

• Can be used for inflammatory and allergic conditions including arthritis, fatigue, snake bites, or systemic stress responses

Contraindications

Do not use in animals with:

• Chronic nephritis
• Congestive heart failure
• Diabetes mellitus
• Cushing’s syndrome
• Osteoporosis
• During the viremic stage of viral infections

Undesirable Effects

Administration during the last trimester of pregnancy may induce premature parturition and may lead to dystocia, fetal death, retained placenta, and subsequent metritis.

Special Precautions for Use

• For veterinary use only
• Use only under veterinary supervision, especially in pregnant animals or those with underlying metabolic conditions

Posology and Method of Administration

• Cattle and horses: 1 ml per 25 kg body weight, intramuscular (IM) or intravenous (IV)
• Dogs and cats: 1 ml per 10 kg body weight, IM or IV
  Dosage and duration should be determined by a veterinarian based on the clinical condition.

Overdose

No significant adverse effects have been reported at therapeutic doses.

Withdrawal Periods

• Meat: 21 days
• Milk: 3 days

Special Safety Precautions for the Person Administering the Product

No special precautions are required under normal use conditions.

Storage Instructions

• Store in a dry place, below 30°C
• Do not refrigerate
• Protect from light

Packaging

Available in 50 ml amber glass vials

For veterinary use only. Consult a veterinarian before use.