Composition

Each 1 ml contains:

• Tylosin ( as tartrate)  50mg

* Equivalent to 0.05 g tylosin with 5% overage to compensate for processing loss

Pharmaceutical Form

Clear pale yellow intramuscular injectable solution

Pharmacological Properties

Tylosin is an antibiotic produced by Streptomyces fradiae, belonging to the actinomycetes group. It exhibits strong antibacterial activity primarily against Gram-positive bacteria. It is also effective against certain spirochetes, some Gram-negative microorganisms (excluding coliforms), large viruses, and specific Mycoplasma species. This broad yet targeted activity makes Tylodad a valuable treatment option for various bacterial infections.

Target Species

Cattle, camels, sheep, goats, dogs, and cats

Indications for Use

Tylodad 5% Injection is indicated for the treatment of bacterial infections including:

• Pneumonia caused by Pasteurella multocida and Corynebacterium pyogenes
• Foot rot (necrotic pododermatitis) and diphtheria caused by Spherophorus necrophorus
• Metritis caused by Corynebacterium pyogenes
• Acute mastitis due to Streptococcus and Staphylococcus species

In sheep and goats, it treats early stages of contagious agalactia caused by Mycoplasma agalactiae and caprine pleuropneumonia caused by Mycoplasma mycoides.

In dogs and cats, Tylodad effectively manages upper respiratory infections (tracheobronchitis, bronchitis, laryngitis, tracheitis), feline pneumonitis, cellulitis, pneumonia, otitis externa, metritis, interdigital cysts, tonsillitis, leptospirosis, secondary bacterial infections linked to viral diseases, and supports recovery after surgical procedures or injuries.

Contraindications

• Do not use in horses or other equines, as tylosin administration can be fatal.

Undesirable Effects

None reported when used as directed

Special Precautions for Use

• Do not mix Tylodad 5% Injection with other parenteral solutions to avoid precipitation of the active ingredient.

Posology and Method of Administration

Administer intramuscularly as follows:

• Cattle, camels, sheep, and goats: 8 mg tylosin per 0.45 kg body weight (equivalent to 1 ml per 2.8 kg body weight) once daily. Treatment should continue until 24 hours after signs resolve, not exceeding 5 days.
• Dogs and cats: 3 to 5 mg tylosin per 0.45 kg body weight every 12 to 24 hours as needed.

Overdose

No known adverse effects reported at recommended doses. Monitor animals and consult a veterinarian if overdose is suspected.

Withdrawal Period

• Animals must not be slaughtered within 21 days after the last treatment.
• Milk from treated cows must not be consumed during treatment and for 72 hours after the last dose.
• Milk from treated sheep and goats must not be consumed during treatment and for 48 hours after the last dose.

Special Safety Precautions for the Person Administering the Product

No special precautions beyond standard hygiene and injection safety measures.

Special Precautions for Storage

Store in a dark, dry place below 25°C. Protect from light and freezing.

Packaging

Available in 50 ml, 100 ml, and 250 ml glass vials

For veterinary use only. Consult a veterinarian before use.