Composition
Each 1 g contains:
- Sulphadiazine Sodium 400 mg
- Trimethoprim 80 mg
Pharmacological Properties
Dadprim is a synergistic combination of Sulphadiazine and Trimethoprim. While each compound is bacteriostatic on its own, their combination results in a bactericidal effect by inhibiting sequential steps in bacterial folic acid synthesis.
This dual-action mechanism makes Dadprim highly effective against a wide range of pathogens, particularly in cases where resistance to other antimicrobials is a concern.
Target Species
- Poultry
- Pre-ruminants (calves, lambs, kids)
Indications for Use
Dadprim is indicated for the treatment of infections caused by susceptible Gram-positive and Gram-negative bacteria, including:
- Salmonella spp.
- Escherichia coli
- Klebsiella spp.
- Proteus spp.
- Haemophilus spp. (Infectious Coryza)
- Pasteurella spp.
- Clostridium spp.
- Corynebacterium spp.
- Streptococcus spp.
- Staphylococcus spp.
It is also effective in treating omphalitis and various enteric and respiratory infections in young animals and poultry.
Contraindications
No specific contraindications have been reported when used as recommended.
Undesirable Effects
No undesirable effects are expected under normal dosage conditions.
Posology and Method of Administration
- Poultry: 1 g per 4 liters of drinking water daily, for 3 to 5 days.
- Pre-ruminants (calves, lambs, kids): 1 g per 10–15 kg of body weight daily, for 4 to 10 days.
Administration should be done via drinking water or mixed with milk or feed, depending on the species.
Overdose
No adverse effects are expected when used according to the recommended dosages.
Withdrawal Period
Animals and birds should not be slaughtered for human consumption within 5 days of the last treatment.
Special Safety Precautions for the Person Administering the Product
No specific precautions are required during normal use.
Special Precautions for Storage
- Store in a dry place below 30°C.
- Keep out of reach of children.
For veterinary use only. Consult a veterinarian before use.
